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Choice of selectable marker affects recombinant protein expression in cells and exosomes

Transgenic mammalian cells are used for numerous research, pharmaceutical, industrial, and clinical purposes, and dominant selectable markers are often used to enable the selection of transgenic cell lines. Using HEK293 cells, we show here that the choice of selectable marker gene has a significant...

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Detalles Bibliográficos
Autores principales:	Guo, Chenxu, Fordjour, Francis K., Tsai, Shang Jui, Morrell, James C., Gould, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258971/ https://www.ncbi.nlm.nih.gov/pubmed/34051235 http://dx.doi.org/10.1016/j.jbc.2021.100838

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