H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve

The induction of nerve injury response genes in Schwann cells depends on both transcriptional and epigenomic reprogramming. The nerve injury response program is regulated by the repressive histone mark H3K27 trimethylation (H3K27me3), deposited by Polycomb repressive complex 2 (PRC2). Loss of PRC2 f...

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Detalles Bibliográficos
Autores principales: Duong, Phu, Ma, Ki H., Ramesh, Raghu, Moran, John J., Won, Seongsik, Svaren, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258988/
https://www.ncbi.nlm.nih.gov/pubmed/34090875
http://dx.doi.org/10.1016/j.jbc.2021.100852

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