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Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?

The novel coronavirus disease 2019 (COVID-19) has pushed the medical system to its breaking point. While the virus does not discriminate, the elderly and those with comorbidities, including hypertension severe obesity, diabetes mellitus, coronary disease, pneumonia and dementia, are at a greater ris...

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Detalles Bibliográficos
Autores principales: John, Albin, Ali, Kiran, Marsh, Harrison, Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259043/
https://www.ncbi.nlm.nih.gov/pubmed/34242809
http://dx.doi.org/10.1016/j.arr.2021.101406
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author John, Albin
Ali, Kiran
Marsh, Harrison
Reddy, P. Hemachandra
author_facet John, Albin
Ali, Kiran
Marsh, Harrison
Reddy, P. Hemachandra
author_sort John, Albin
collection PubMed
description The novel coronavirus disease 2019 (COVID-19) has pushed the medical system to its breaking point. While the virus does not discriminate, the elderly and those with comorbidities, including hypertension severe obesity, diabetes mellitus, coronary disease, pneumonia and dementia, are at a greater risk for adverse outcomes due to COVID-19. While many people navigate their new normal, the question of what the long-lasting effects of the pandemic may be, lingers. To investigate how vulnerable populations are affected by the pandemic, we focused on Alzheimer’s disease, a vector to understanding how the virus has impacted AD progression and risk via aging. By assessing the effect of COVID-19 on AD patients, we explore genetics, metabolism, and lifestyle factors in both COVID-19 and Alzheimer’s disease that can work synergistically to precipitate adverse outcomes. This article also discusses how age-related conditions and/or age-related comorbidities susceptible to COVID-19. We also discuss possible healthy lifestyle factors reduce and/or combat COVID-19 now and in the future.
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spelling pubmed-82590432021-07-06 Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19? John, Albin Ali, Kiran Marsh, Harrison Reddy, P. Hemachandra Ageing Res Rev Review The novel coronavirus disease 2019 (COVID-19) has pushed the medical system to its breaking point. While the virus does not discriminate, the elderly and those with comorbidities, including hypertension severe obesity, diabetes mellitus, coronary disease, pneumonia and dementia, are at a greater risk for adverse outcomes due to COVID-19. While many people navigate their new normal, the question of what the long-lasting effects of the pandemic may be, lingers. To investigate how vulnerable populations are affected by the pandemic, we focused on Alzheimer’s disease, a vector to understanding how the virus has impacted AD progression and risk via aging. By assessing the effect of COVID-19 on AD patients, we explore genetics, metabolism, and lifestyle factors in both COVID-19 and Alzheimer’s disease that can work synergistically to precipitate adverse outcomes. This article also discusses how age-related conditions and/or age-related comorbidities susceptible to COVID-19. We also discuss possible healthy lifestyle factors reduce and/or combat COVID-19 now and in the future. Published by Elsevier B.V. 2021-09 2021-07-06 /pmc/articles/PMC8259043/ /pubmed/34242809 http://dx.doi.org/10.1016/j.arr.2021.101406 Text en © 2021 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
John, Albin
Ali, Kiran
Marsh, Harrison
Reddy, P. Hemachandra
Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?
title Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?
title_full Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?
title_fullStr Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?
title_full_unstemmed Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?
title_short Can healthy lifestyle reduce disease progression of Alzheimer’s during a global pandemic of COVID-19?
title_sort can healthy lifestyle reduce disease progression of alzheimer’s during a global pandemic of covid-19?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259043/
https://www.ncbi.nlm.nih.gov/pubmed/34242809
http://dx.doi.org/10.1016/j.arr.2021.101406
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