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Sacituzumab govitecan and trastuzumab deruxtecan: two new antibody–drug conjugates in the breast cancer treatment landscape

BACKGROUND: Two new antibody–drug conjugates (ADCs) containing a topoisomerase I inhibitor payload have recently emerged in the breast cancer (BC) treatment landscape. Sacituzumab govitecan-hziy (SG) is a first-in-class anti-trophoblast cell-surface antigen 2 ADC approved for pretreated metastatic t...

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Detalles Bibliográficos
Autores principales:	Adams, E., Wildiers, H., Neven, P., Punie, K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259232/ https://www.ncbi.nlm.nih.gov/pubmed/34225076 http://dx.doi.org/10.1016/j.esmoop.2021.100204

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