Milan ultrasound criteria are accurate in assessing disease activity in ulcerative colitis: external validation

INTRODUCTION: The aim of this study was to provide an external validation of bowel ultrasound (US) predictors of activity in ulcerative colitis (UC) and quantitative Milan Ultrasound Criteria (MUC). METHODS: Forty‐three consecutive patients with UC (16 in endoscopic remission and 27 with endoscopic...

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Detalles Bibliográficos
Autores principales: Allocca, Mariangela, Filippi, Elisabetta, Costantino, Andrea, Bonovas, Stefanos, Fiorino, Gionata, Furfaro, Federica, Peyrin‐Biroulet, Laurent, Fraquelli, Mirella, Caprioli, Flavio, Danese, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259285/
https://www.ncbi.nlm.nih.gov/pubmed/33349199
http://dx.doi.org/10.1177/2050640620980203
Descripción
Sumario:INTRODUCTION: The aim of this study was to provide an external validation of bowel ultrasound (US) predictors of activity in ulcerative colitis (UC) and quantitative Milan Ultrasound Criteria (MUC). METHODS: Forty‐three consecutive patients with UC (16 in endoscopic remission and 27 with endoscopic activity) underwent bowel US and colonoscopy in a tertiary referral inflammatory bowel disease unit. RESULTS: An MUC score >6.2 discriminated patients with active versus non‐active UC with a sensitivity of 0.85 (95% confidence interval (CI) 0.66–0.96), specificity of 0.94 (95% CI 0.70–0.99) and an area under the curve of 0.902 (95% CI 0.772–0.971) in complete agreement with the derivation study. CONCLUSION: The external validation of MUC confirms that it is an accurate tool for assessing disease activity in patients with UC.

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