Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin

BACKGROUND: CCR6 chemokine receptor is an important target in inflammatory diseases. Th17 cells express CCR6 and a number of inflammatory cytokines, including IL-17 and IL-22, which are involved in the propagation of inflammatory immune responses. CCR6 antagonist would be a potential treatment for i...

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Detalles Bibliográficos
Autores principales: Gómez-Melero, Sara, García-Maceira, Fé Isabel, García-Maceira, Tania, Luna-Guerrero, Verónica, Montero-Peñalvo, Gracia, Túnez-Fiñana, Isaac, Paz-Rojas, Elier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259436/
https://www.ncbi.nlm.nih.gov/pubmed/34225700
http://dx.doi.org/10.1186/s12896-021-00699-2

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