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Mutations of METTL3 predict response to neoadjuvant chemotherapy in muscle-invasive bladder cancer

BACKGROUND AND AIM: Neoadjuvant chemotherapy (NAC) followed by radical cystectomy is the current gold standard treatment for muscle-invasive urothelial bladder cancer (MIBC). Nonetheless, some MIBC patients showed limited pathological response after NAC. Herein, we used whole-exome sequencing (WES)...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Shen, Zongyi, Jin, Di, Zhang, Nan, Wang, Yue, Lei, Wanjun, Zhang, Zhiming, Chen, Haige, Naz, Faiza, Xu, Lida, Wang, Lei, Wang, Shihui, Su, Xin, Yu, Changyuan, Li, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259609/
https://www.ncbi.nlm.nih.gov/pubmed/34239995