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A Negative Feedback Loop in Ultraviolet A-Induced Senescence in Human Dermal Fibroblasts Formed by SPCA1 and MAPK

Secretory pathway calcium ATPase 1 (SPCA1) is a calcium pump localized specifically to the Golgi. Its effects on UVA-induced senescence have never been examined. In our study, expression of SPCA1 was increased in UVA-irradiated human dermal fibroblasts (HDFs) by activating mitogen-activated protein...

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Detalles Bibliográficos
Autores principales: Xie, Hongfu, Xiao, Xiao, Yi, Yuxin, Deng, Mingxing, Li, Peihui, Jian, Dan, Deng, Zhili, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259626/
https://www.ncbi.nlm.nih.gov/pubmed/34239867
http://dx.doi.org/10.3389/fcell.2020.597993

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