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Naturally circulating pertactin-deficient Bordetella pertussis strains induce distinct gene expression and inflammatory signatures in human dendritic cells

Respiratory infections caused by Bordetella pertussis are reemerging despite high pertussis vaccination coverage. Since the introduction of the acellular pertussis vaccine in the late twentieth century, circulating B. pertussis strains increasingly lack expression of the vaccine component pertactin...

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Detalles Bibliográficos
Autores principales: Kroes, Michiel M., Miranda-Bedate, Alberto, Hovingh, Elise S., Jacobi, Ronald, Schot, Corrie, Pupo, Elder, Raeven, René H. M., van der Ark, Arno A. J., van Putten, Jos P. M., de Wit, Jelle, Mariman, Rob, Pinelli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259873/
https://www.ncbi.nlm.nih.gov/pubmed/34132167
http://dx.doi.org/10.1080/22221751.2021.1943537