Cargando…

Effective Antitumor of Orally Intestinal Targeting Penetrating Peptide-Loaded Tyroserleutide/PLGA Nanoparticles in Hepatocellular Carcinoma

PURPOSE: Hepatocellular carcinoma (HCC) is a common malignant tumor that seriously threatens human life and health. Currently, the majority of antitumor drugs are administered in an injectable manner, which can cause pain and side effects to patients. Objective of this study is to establish an effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Chenjun, Wei, Tiantian, Hua, Yingying, Wang, Zhongjie, Zhang, Liefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259945/ https://www.ncbi.nlm.nih.gov/pubmed/34239301 http://dx.doi.org/10.2147/IJN.S315713

Ejemplares similares

Tripeptide tyroserleutide plus doxorubicin: therapeutic synergy and side effect attenuation
por: Zhu, Zhi-feng, et al.
Publicado: (2008)

A comparison of acyl-moieties for noncovalent functionalization of PLGA and PEG-PLGA nanoparticles with a cell-penetrating peptide
por: Paulino da Silva Filho, Omar, et al.
Publicado: (2021)

Collagen/Chitosan Complexes: Preparation, Antioxidant Activity, Tyrosinase Inhibition Activity, and Melanin Synthesis
por: Hua, Yingying, et al.
Publicado: (2020)

Docetaxel Loaded PEG-PLGA Nanoparticles: Optimized Drug Loading, In-vitro Cytotoxicity and In-vivo Antitumor Effect
por: Noori Koopaei, Mona, et al.
Publicado: (2014)

Structural Optimization of Platinum Drugs to Improve the Drug-Loading and Antitumor Efficacy of PLGA Nanoparticles
por: Sokol, Maria B., et al.
Publicado: (2022)

Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles
por: Colzani, Barbara, et al.
Publicado: (2018)

The Idiosyncratic Efficacy of Spironolactone-Loaded PLGA Nanoparticles Against Murine Intestinal Schistosomiasis
por: Abd El Hady, Walaa Ebrahim, et al.
Publicado: (2023)

The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells
por: Xu, Yuanyuan, et al.
Publicado: (2016)

Mithramycin-loaded mPEG-PLGA nanoparticles exert potent antitumor efficacy against pancreatic carcinoma
por: Liu, Xu-Jie, et al.
Publicado: (2017)

Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Therapeutic effects of tyroserleutide on lung metastasis of human hepatocellular carcinoma SK-HEP-1 and its mechanism affecting ICAM-1 and MMP-2 and -9
por: Che, Xuchun, et al.
Publicado: (2018)

The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo
por: Li, Zhenbao, et al.
Publicado: (2017)

Effect of Dexamethasone-Loaded PLGA Nanoparticles on Oral Mucositis Induced by 5-Fluorouracil
por: Ribeiro, Susana Barbosa, et al.
Publicado: (2021)

Preparation, characterization and immunological evaluation: canine parvovirus synthetic peptide loaded PLGA nanoparticles
por: Derman, Serap, et al.
Publicado: (2015)

Development of Peptide Targeted PLGA-PEGylated Nanoparticles Loading Licochalcone-A for Ocular Inflammation
por: Galindo, Ruth, et al.
Publicado: (2022)

Preparation, Characterization, and Biological Evaluation of a Hydrophilic Peptide Loaded on PEG-PLGA Nanoparticles
por: Marinelli, Lisa, et al.
Publicado: (2022)

Enhanced antitumor efficacy in colon cancer using EGF functionalized PLGA nanoparticles loaded with 5-Fluorouracil and perfluorocarbon
por: Wu, Pingping, et al.
Publicado: (2020)

Therapeutic Effects of Tyroserleutide on Lung Metastasis of Human Hepatocellular Carcinoma SK-HEP-1 and Its Mechanism Affecting ICAM-1 and MMP-2 and -9 [Retraction]
Publicado: (2023)

Oral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy
por: Chen, Hongbo, et al.
Publicado: (2010)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei, Pedram, et al.
Publicado: (2017)

Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model
por: Al-Thani, Hissa F., et al.
Publicado: (2022)

Dual Agent Loaded PLGA Nanoparticles Enhanced Antitumor Activity in a Multidrug-Resistant Breast Tumor Eenograft Model
por: Chen, Yan, et al.
Publicado: (2014)

Ifosfamide-loaded poly (lactic-co-glycolic acid) PLGA-dextran polymeric nanoparticles to improve the antitumor efficacy in Osteosarcoma
por: Chen, Bin, et al.
Publicado: (2015)

Curcumin Loaded-PLGA Nanoparticles Conjugated with Tet-1 Peptide for Potential Use in Alzheimer's Disease
por: Mathew, Anila, et al.
Publicado: (2012)

Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics
por: Ünal, Sedat, et al.
Publicado: (2022)

Local penetration of doxorubicin via intrahepatic implantation of PLGA based doxorubicin-loaded implants
por: Gao, Li, et al.
Publicado: (2019)

Design and Optimization of PLGA-Based Diclofenac Loaded Nanoparticles
por: Cooper, Dustin L., et al.
Publicado: (2014)

Unraveling the cytotoxic potential of Temozolomide loaded into PLGA nanoparticles
por: Jain, Darshana S, et al.
Publicado: (2014)

The Potential of Atractylodin-Loaded PLGA Nanoparticles as Chemotherapeutic for Cholangiocarcinoma
por: Muhamad, Nadda, et al.
Publicado: (2020)

Hydrotalcite–PLGA composite nanoparticles for loading and delivery of danshensu
por: Pu, Lihui, et al.
Publicado: (2020)

Drug-loaded PEG-PLGA nanoparticles for cancer treatment
por: Zhang, Dan, et al.
Publicado: (2022)

Fabrication and in vivo evaluation of Nelfinavir loaded PLGA nanoparticles for enhancing oral bioavailability and therapeutic effect
por: Venkatesh, D. Nagasamy, et al.
Publicado: (2015)

Curcumin-loaded PLGA-PEG nanoparticles conjugated with B6 peptide for potential use in Alzheimer’s disease
por: Fan, Shengnuo, et al.
Publicado: (2018)

Improved Controlled Release and Brain Penetration of the Small Molecule S14 Using PLGA Nanoparticles †
por: Nozal, Vanesa, et al.
Publicado: (2021)

Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats
por: Rong, Xianfang, et al.
Publicado: (2018)

Endostar-loaded PEG-PLGA nanoparticles: in vitro and in vivo evaluation
por: Hu, Sanyuan, et al.
Publicado: (2010)

Development and optimization of quercetin-loaded PLGA nanoparticles by experimental design
por: TEFAS, LUCIA RUXANDRA, et al.
Publicado: (2015)

Investigation of Effective Parameters on Size of Paclitaxel Loaded PLGA Nanoparticles
por: Madani, Fatemeh, et al.
Publicado: (2018)

Antileishmanial Activity of Amphotericin B-loaded-PLGA Nanoparticles: An Overview
por: Palma, Ernesto, et al.
Publicado: (2018)

Antioxidant Activity and Hemocompatibility Study of Quercetin Loaded Plga Nanoparticles
por: Derman, Serap, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_92u9coa395jafnk38j5qnhcjna