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Mortality and morbidity of asthma and chronic obstructive pulmonary disease associated with ambient environment in metropolitans in Taiwan

BACKGROUND: This study investigated risks of mortality from and morbidity (emergency room visits (ERVs) and outpatient visits) of asthma and chronic obstructive pulmonary disease (COPD) associated with extreme temperatures, fine particulate matter (PM(2.5)), and ozone (O(3)) by sex, and age, from 20...

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Detalles Bibliográficos
Autores principales: Zafirah, Yasmin, Lin, Yu-Kai, Andhikaputra, Gerry, Deng, Li-Wen, Sung, Fung-Chang, Wang, Yu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259956/
https://www.ncbi.nlm.nih.gov/pubmed/34228742
http://dx.doi.org/10.1371/journal.pone.0253814
Descripción
Sumario:BACKGROUND: This study investigated risks of mortality from and morbidity (emergency room visits (ERVs) and outpatient visits) of asthma and chronic obstructive pulmonary disease (COPD) associated with extreme temperatures, fine particulate matter (PM(2.5)), and ozone (O(3)) by sex, and age, from 2005 to 2016 in 6 metropolitan cities in Taiwan. METHODS: The distributed lag non-linear model was employed to assess age (0–18, 19–39, 40–64, and 65 years and above), sex-cause-specific deaths, ERVs, and outpatient visits associated with extreme high (99(th) percentile) and low (5(th) percentile) temperatures and PM(2.5) and O(3) concentrations at 90(th) percentile. Random-effects meta-analysis was adopted to investigate cause-specific pooled relative risk (RR) and 95% confidence intervals (CI) for the whole studied areas. RESULTS: Only the mortality risk of COPD in the elderly men was significantly associated with the extreme low temperatures. Exposure to the 90(th) percentile PM(2.5) was associated with outpatient visits for asthma in 0–18 years old boys [RR = 1.15 (95% CI: 1.09–1.22)]. Meanwhile, significant elevation of ERVs of asthma for females aged 40–64 years was associated with exposure to ozone, with the highest RR of 1.21 (95% CI: 1.05–1.39). CONCLUSIONS: This study identified vulnerable subpopulations who were at risk to extreme events associated with ambient environments deserving further evaluation for adaptation.