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Structural and functional diversity among Type III restriction-modification systems that confer host DNA protection via methylation of the N4 atom of cytosine

We report a new subgroup of Type III Restriction-Modification systems that use m4C methylation for host protection. Recognition specificities for six such systems, each recognizing a novel motif, have been determined using single molecule real-time DNA sequencing. In contrast to all previously chara...

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Detalles Bibliográficos
Autores principales:	Murray, Iain A., Luyten, Yvette A., Fomenkov, Alexey, Dai, Nan, Corrêa, Ivan R., Farmerie, William G., Clark, Tyson A., Korlach, Jonas, Morgan, Richard D., Roberts, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259958/ https://www.ncbi.nlm.nih.gov/pubmed/34228724 http://dx.doi.org/10.1371/journal.pone.0253267

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