Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia

Herpes zoster, the result of varicella-zoster virus (VZV) reactivation, is frequently complicated by difficult-to-treat chronic pain states termed postherpetic neuralgia (PHN). While there are no animal models of VZV-induced pain following viral reactivation, subcutaneous VZV inoculation of the rat...

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Detalles Bibliográficos
Autores principales: Warner, Benjamin E., Yee, Michael B., Zhang, Mingdi, Hornung, Rebecca S., Kaufer, Benedikt B., Visalli, Robert J., Kramer, Phillip R., Goins, William F., Kinchington, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259975/
https://www.ncbi.nlm.nih.gov/pubmed/34228767
http://dx.doi.org/10.1371/journal.ppat.1009689

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