Cargando…

The Integrin Signaling Network Promotes Axon Regeneration via the Src–Ephexin–RhoA GTPase Signaling Axis

Axon regeneration is an evolutionarily conserved process essential for restoring the function of damaged neurons. In Caenorhabditis elegans hermaphrodites, initiation of axon regeneration is regulated by the RhoA GTPase–ROCK (Rho-associated coiled-coil kinase)–regulatory nonmuscle myosin light-chain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sakai, Yoshiki, Tsunekawa, Mayuka, Ohta, Kohei, Shimizu, Tatsuhiro, Pastuhov, Strahil, Hanafusa, Hiroshi, Hisamoto, Naoki, Matsumoto, Kunihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260174/ https://www.ncbi.nlm.nih.gov/pubmed/33963050 http://dx.doi.org/10.1523/JNEUROSCI.2456-20.2021

Ejemplares similares

Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
por: Hisamoto, Naoki, et al.
Publicado: (2018)

BRCA1–BARD1 Regulates Axon Regeneration in Concert with the Gqα–DAG Signaling Network
por: Sakai, Yoshiki, et al.
Publicado: (2021)

TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor
por: Sakai, Yoshiki, et al.
Publicado: (2019)

Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor
por: Shimizu, Tatsuhiro, et al.
Publicado: (2021)

The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK–JNK Signaling Pathway in Axon Regeneration
por: Hisamoto, Naoki, et al.
Publicado: (2016)

MAP kinase cascades regulating axon regeneration in C. elegans
por: PASTUHOV, Strahil Iv., et al.
Publicado: (2015)

Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling
por: Pastuhov, Strahil Iv., et al.
Publicado: (2012)

CDK14 Promotes Axon Regeneration by Regulating the Noncanonical Wnt Signaling Pathway in a Kinase-Independent Manner
por: Hisamoto, Naoki, et al.
Publicado: (2021)

Rho Gtpases: Integrating Integrin Signaling
por: Ridley, Anne
Publicado: (2000)

Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans
por: Alam, Tanimul, et al.
Publicado: (2016)

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases
por: Clark, Edwin A., et al.
Publicado: (1998)

Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation
por: Roh-Johnson, Minna, et al.
Publicado: (2013)

Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling
por: Inaba, Hironori, et al.
Publicado: (2021)

The RhoA GTPase regulates Type I Interferon Signaling in Systemic lupus erythematosus
por: Fan, Wei, et al.
Publicado: (2023)

A Small GTPase, RhoA, Inhibits Bacterial Infection Through Integrin Mediated Phagocytosis in Invertebrates
por: Xu, Ji-Dong, et al.
Publicado: (2018)

Protocol for structural and biochemical analyses of RhoA GTPase
por: Lin, Yuan, et al.
Publicado: (2021)

The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals
por: Dubash, Adi D., et al.
Publicado: (2011)

RhoA of the Rho Family Small GTPases Is Essential for B Lymphocyte Development
por: Zhang, Shuangmin, et al.
Publicado: (2012)

The Intermolecular Interaction of Ephexin4 Leads to Autoinhibition by Impeding Binding of RhoG
por: Kim, Kwanhyeong, et al.
Publicado: (2018)

Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling
por: Zhang, Yan-Li, et al.
Publicado: (2018)

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020)

RhoA Signaling in Neurodegenerative Diseases
por: Schmidt, Sissel Ida, et al.
Publicado: (2022)

Role of Small GTPase RhoA in DNA Damage Response
por: Cheng, Chibin, et al.
Publicado: (2021)

Structure of human TRPV4 in complex with GTPase RhoA
por: Nadezhdin, Kirill D., et al.
Publicado: (2023)

Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
por: Werner, Erica, et al.
Publicado: (2002)

Roles of the small GTPases RhoA and Rac1 in cell behavior
por: Otey, Carol, et al.
Publicado: (2009)

The Small GTPase RhoA Is Required for Proper Locomotor Circuit Assembly
por: Mulherkar, Shalaka, et al.
Publicado: (2013)

RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors
por: Zhou, Xuan, et al.
Publicado: (2013)

RhoA GTPase inhibition organizes contraction during epithelial morphogenesis
por: Mason, Frank M., et al.
Publicado: (2016)

Regulation of smooth muscle contraction by monomeric non‐RhoA GTPases
por: Li, Bingsheng, et al.
Publicado: (2020)

Conserved roles for yeast Rho1 and mammalian RhoA GTPases in clathrin-independent endocytosis
por: Prosser, Derek C., et al.
Publicado: (2012)

Rho GTPase signalling in cell migration
por: Ridley, Anne J
Publicado: (2015)

Multifaceted Rho GTPase Signaling at the Endomembranes
por: Phuyal, Santosh, et al.
Publicado: (2019)

Rho GTPase signaling in rheumatic diseases
por: Zeng, Ruijie, et al.
Publicado: (2021)

PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling
por: Chen, Hualin, et al.
Publicado: (2023)

Histidine dephosphorylation of the Gβ protein GPB‐1 promotes axon regeneration in C. elegans
por: Sakai, Yoshiki, et al.
Publicado: (2022)

Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via α6β1 Integrin-Fyn-RhoA-ROCK Signaling
por: Nakashima, Yoshiki, et al.
Publicado: (2022)

Emerging Roles of Ephexins in Physiology and Disease
por: Kim, Kwanhyeong, et al.
Publicado: (2019)

Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA
por: Thakar, Ketan, et al.
Publicado: (2017)

Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion
por: Hetmanski, Joseph H.R., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_t4is8ampap6lf8km8bih2r1ho0