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Heroin-Induced Acute Pancreatitis
Heroin-induced pancreatitis (HIP) is rare with only a few cases reported previously in the literature and the pathophysiology mechanism is yet to be investigated. We present two cases of acute pancreatitis (AP) in the setting of acute heroin (diacetylmorphine) intoxication. Both patients presented w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260205/ https://www.ncbi.nlm.nih.gov/pubmed/34262808 http://dx.doi.org/10.7759/cureus.15470 |
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author | Ciobanu, Camelia Jadav, Raja Shekar Colon Ramos, Ana Sequeira Gross, Harry G Brazzarola, Carlos |
author_facet | Ciobanu, Camelia Jadav, Raja Shekar Colon Ramos, Ana Sequeira Gross, Harry G Brazzarola, Carlos |
author_sort | Ciobanu, Camelia |
collection | PubMed |
description | Heroin-induced pancreatitis (HIP) is rare with only a few cases reported previously in the literature and the pathophysiology mechanism is yet to be investigated. We present two cases of acute pancreatitis (AP) in the setting of acute heroin (diacetylmorphine) intoxication. Both patients presented with nausea, vomiting and severe abdominal pain after intranasal heroin use. On laboratory analysis were found to have elevated serum lipase, positive urine toxicology for opioids, without any other obvious causes for AP. Both patients had a full recovery with supportive treatment. As a general approach, drug-induced pancreatitis is a diagnosis of exclusion and a high index of suspicion is required when the most common etiologies are ruled out. |
format | Online Article Text |
id | pubmed-8260205 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-82602052021-07-13 Heroin-Induced Acute Pancreatitis Ciobanu, Camelia Jadav, Raja Shekar Colon Ramos, Ana Sequeira Gross, Harry G Brazzarola, Carlos Cureus Internal Medicine Heroin-induced pancreatitis (HIP) is rare with only a few cases reported previously in the literature and the pathophysiology mechanism is yet to be investigated. We present two cases of acute pancreatitis (AP) in the setting of acute heroin (diacetylmorphine) intoxication. Both patients presented with nausea, vomiting and severe abdominal pain after intranasal heroin use. On laboratory analysis were found to have elevated serum lipase, positive urine toxicology for opioids, without any other obvious causes for AP. Both patients had a full recovery with supportive treatment. As a general approach, drug-induced pancreatitis is a diagnosis of exclusion and a high index of suspicion is required when the most common etiologies are ruled out. Cureus 2021-06-05 /pmc/articles/PMC8260205/ /pubmed/34262808 http://dx.doi.org/10.7759/cureus.15470 Text en Copyright © 2021, Ciobanu et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Ciobanu, Camelia Jadav, Raja Shekar Colon Ramos, Ana Sequeira Gross, Harry G Brazzarola, Carlos Heroin-Induced Acute Pancreatitis |
title | Heroin-Induced Acute Pancreatitis |
title_full | Heroin-Induced Acute Pancreatitis |
title_fullStr | Heroin-Induced Acute Pancreatitis |
title_full_unstemmed | Heroin-Induced Acute Pancreatitis |
title_short | Heroin-Induced Acute Pancreatitis |
title_sort | heroin-induced acute pancreatitis |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260205/ https://www.ncbi.nlm.nih.gov/pubmed/34262808 http://dx.doi.org/10.7759/cureus.15470 |
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