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Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci
Genome-wide association studies have identified hundreds of loci associated with coronary artery disease (CAD). Many of these loci are enriched in cisregulatory elements but not linked to cardiometabolic risk factors nor to candidate causal genes, complicating their functional interpretation. OBJECT...
Autores principales: | Örd, Tiit, Õunap, Kadri, Stolze, Lindsey K., Aherrahrou, Redouane, Nurminen, Valtteri, Toropainen, Anu, Selvarajan, Ilakya, Lönnberg, Tapio, Aavik, Einari, Ylä-Herttuala, Seppo, Civelek, Mete, Romanoski, Casey E., Kaikkonen, Minna U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260472/ https://www.ncbi.nlm.nih.gov/pubmed/34024118 http://dx.doi.org/10.1161/CIRCRESAHA.121.318971 |
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