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Anti-pruritic effect of nemolizumab in hemodialysis patients with uremic pruritus: a phase II, randomized, double-blind, placebo-controlled clinical study

BACKGROUND: The pathophysiology of uremic pruritus (UP), which is characterized by systemic and intractable itching, remains unclear. As interleukin (IL)-31 may be involved, we conducted a phase II, randomized, controlled study to evaluate nemolizumab (anti-IL-31 receptor A antibody) in Japanese hem...

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Detalles Bibliográficos
Autores principales: Kinugasa, Eriko, Igawa, Ken, Shimada, Hisaki, Kondo, Morihiro, Funakoshi, Satoshi, Imada, Naoki, Itami, Noritomo, Fukazawa, Naoki, Takubo, Ryoko, Kawata, Yuichi, Murota, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260520/
https://www.ncbi.nlm.nih.gov/pubmed/33754202
http://dx.doi.org/10.1007/s10157-021-02047-2