Therapierefraktäre Anämie bei einem 35-jährigen Dialysepatienten nach Herztransplantation

This article presents a case of pure red cell aplasia in a 35-year-old heart transplant recipient on chronic hemodialysis. Elevated parvovirus B19 immunoglobulin M blood levels were detected along with a high viral load of 80 billion IU/ml quantified by polymerase chain reaction. Bone marrow examina...

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Detalles Bibliográficos
Autores principales: Schröder, Christoph, Roeles, Johannes, Schwarzer, Adrian, Heuser, Michael, Retzlaff, Jennifer, Hiß, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2021
Materias:
Kasuistiken
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260535/
https://www.ncbi.nlm.nih.gov/pubmed/33580307
http://dx.doi.org/10.1007/s00108-021-00955-9
Descripción
Sumario:This article presents a case of pure red cell aplasia in a 35-year-old heart transplant recipient on chronic hemodialysis. Elevated parvovirus B19 immunoglobulin M blood levels were detected along with a high viral load of 80 billion IU/ml quantified by polymerase chain reaction. Bone marrow examination revealed giant proerythroblasts confirming parvovirus B19 infection. High-dose intravenous immunoglobulin was used for treatment. Anaemia had significantly improved 4 weeks later. Parvovirus B19 infection should be excluded in organ transplant recipients with anaemia due to ineffective erythropoiesis.

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