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Initial impact of SARS-Cov-2 vaccination on healthcare workers in Italy– Update on the 28th of March 2021

In Italy, the COVID-19 vaccination campaign started in December 2020 with the vaccination of healthcare workers (HCW). To analyse the real-life impact that vaccination is having on this population group, we measured the association between week of diagnosis and HCW status using log-binomial regressi...

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Detalles Bibliográficos
Autores principales: Mateo-Urdiales, Alberto, Del Manso, Martina, Andrianou, Xanthi, Spuri, Matteo, D'Ancona, Fortunato, Filia, Antonietta, Rota, Maria Cristina, Petrone, Daniele, Vescio, Maria Fenicia, Riccardo, Flavia, Bella, Antonino, Pezzotti, Patrizio, Fabiani, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260579/
https://www.ncbi.nlm.nih.gov/pubmed/34253419
http://dx.doi.org/10.1016/j.vaccine.2021.07.003
Descripción
Sumario:In Italy, the COVID-19 vaccination campaign started in December 2020 with the vaccination of healthcare workers (HCW). To analyse the real-life impact that vaccination is having on this population group, we measured the association between week of diagnosis and HCW status using log-binomial regression. By the week 22–28 March, we observed a 74% reduction (PPR 0.26; 95% CI 0.22–0.29) in the proportion of cases reported as HCW and 81% reduction in the proportion of symptomatic cases reported as HCW, compared with the week with the lowest proportion of cases among HCWs prior to the vaccination campaign (31 August-7 September). The reduction, both in relative and absolute terms, of COVID-19 cases in HCWs that started around 30 days after the start of the vaccination campaign suggest that COVID-19 vaccines are being effective in preventing infection in this group.