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Cost effectiveness of pharmacogenetic-guided clozapine administration based on risk of HLA variants in Japan and the UK
Pharmacogenetics/pharmacogenomics have enabled the detection of risk of human leukocyte antigen (HLA) variants for clozapine-induced agranulocytosis/granulocytopenia (CIAG). To apply this evidence to the clinical setting, we compared the cost-effectiveness of the proposed “HLA-guided treatment sched...
Autores principales: | Ninomiya, Kohei, Saito, Takeo, Okochi, Tomo, Taniguchi, Satoru, Shimasaki, Ayu, Aoki, Rei, Hata, Takeo, Mushiroda, Taisei, Kanazawa, Tetsufumi, Ikeda, Masashi, Iwata, Nakao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260588/ https://www.ncbi.nlm.nih.gov/pubmed/34230449 http://dx.doi.org/10.1038/s41398-021-01487-4 |
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