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Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5

The chemokine receptor CCR5 plays a vital role in immune surveillance and inflammation. However, molecular details that govern its endogenous chemokine recognition and receptor activation remain elusive. Here we report three cryo-electron microscopy structures of G(i1) protein-coupled CCR5 in a liga...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui, Chen, Kun, Tan, Qiuxiang, Shao, Qiang, Han, Shuo, Zhang, Chenhui, Yi, Cuiying, Chu, Xiaojing, Zhu, Ya, Xu, Yechun, Zhao, Qiang, Wu, Beili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260604/ https://www.ncbi.nlm.nih.gov/pubmed/34230484 http://dx.doi.org/10.1038/s41467-021-24438-5

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