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Both T cell priming in lymph node and CXCR3-dependent migration are the key events for predicting the response of atezolizumab
Anti-PD-L1 antibodies benefit many cancer patients, even those with “non-inflamed tumor”. Determining which patients will benefit remains an important clinical goal. In a non-inflamed tumor mouse model, we found that PD-L1 was highly expressed on antigen-presenting cells (APCs) especially on CD103(+...
Autores principales: | Iwai, Toshiki, Sugimoto, Masamichi, Patil, Namrata S., Bower, Daniel, Suzuki, Miho, Kato, Chie, Yorozu, Keigo, Kurasawa, Mitsue, Shames, David S., Kondoh, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260627/ https://www.ncbi.nlm.nih.gov/pubmed/34230534 http://dx.doi.org/10.1038/s41598-021-93113-y |
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