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Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

LMNA is one of the leading causative genes of genetically inherited dilated cardiomyopathy (DCM). Unlike most DCM-causative genes, which encode sarcomeric or sarcomere-related proteins, LMNA encodes nuclear envelope proteins, lamin A and C, and does not directly associate with contractile function....

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Detalles Bibliográficos
Autores principales: Onoue, Kenji, Wakimoto, Hiroko, Jiang, Jiangming, Parfenov, Michael, DePalma, Steven, Conner, David, Gorham, Joshua, McKean, David, Seidman, Jonathan G., Seidman, Christine E., Saito, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260675/
https://www.ncbi.nlm.nih.gov/pubmed/34250035
http://dx.doi.org/10.3389/fcvm.2021.639148