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Polymorphism in INSR Locus Modifies Risk of Atrial Fibrillation in Patients on Thyroid Hormone Replacement Therapy

AIMS: Atrial fibrillation (AF) is a risk for patients receiving thyroid hormone replacement therapy. No published work has focused on pharmacogenetics relevant to thyroid dysfunction and AF risk. We aimed to assess the effect of L-thyroxine on AF risk stratified by a variation in a candidate gene. M...

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Detalles Bibliográficos
Autores principales:	Soto-Pedre, Enrique, Siddiqui, Moneeza K., Maroteau, Cyrielle, Dawed, Adem Y., Doney, Alex S., Palmer, Colin N. A., Pearson, Ewan R., Leese, Graham P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260687/ https://www.ncbi.nlm.nih.gov/pubmed/34249083 http://dx.doi.org/10.3389/fgene.2021.652878

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