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3-hydroxyanthranic acid increases the sensitivity of hepatocellular carcinoma to sorafenib by decreasing tumor cell stemness
Sorafenib is the FDA-approved first-line target drug for HCC patients. However, sorafenib only confers 3–5 months of survival benefit with <30% of HCC patients. Thus, it is necessary to develop a sensitizer for hepatocellular carcinoma (HCC) to sorafenib. Here, we report that in representative HC...
Autores principales: | Gan, Guifang, Shi, Zhaopeng, Liu, Dan, Zhang, Shaoyi, Zhu, Hui, Wang, Yugang, Mi, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260721/ https://www.ncbi.nlm.nih.gov/pubmed/34230478 http://dx.doi.org/10.1038/s41420-021-00561-6 |
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