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Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV

Left ventricular thrombus typically occurs in patients with impaired left ventricular function such as aneurysm, dilated cardiomyopathy, or post-myocardial infarction. Untreated HIV infection is known to increase the risk of venous thromboembolism and cardiovascular disease. However, the pathophysio...

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Autores principales: Chan, Kok Hoe, Ramahi, Amr, Lim, Su Lin, Ahmed, Eyad, Suleiman, Addi, Slim, Jihad, Shaaban, Hamid S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260751/
https://www.ncbi.nlm.nih.gov/pubmed/34257771
http://dx.doi.org/10.1016/j.radcr.2021.05.068
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author Chan, Kok Hoe
Ramahi, Amr
Lim, Su Lin
Ahmed, Eyad
Suleiman, Addi
Slim, Jihad
Shaaban, Hamid S
author_facet Chan, Kok Hoe
Ramahi, Amr
Lim, Su Lin
Ahmed, Eyad
Suleiman, Addi
Slim, Jihad
Shaaban, Hamid S
author_sort Chan, Kok Hoe
collection PubMed
description Left ventricular thrombus typically occurs in patients with impaired left ventricular function such as aneurysm, dilated cardiomyopathy, or post-myocardial infarction. Untreated HIV infection is known to increase the risk of venous thromboembolism and cardiovascular disease. However, the pathophysiology remains uncertain; some studies have proposed chronic inflammation as the underlying etiology. Nonetheless, left ventricular thrombus is extremely rare among persons living with HIV with no known underlying cardiac disease. Herein, we report an unusual case of a 55-year-old homeless and heterosexual male with past medical history of HIV, who has mildly reduced left ventricular function and a nonmobile, medium size left ventricular thrombus. Patient was initially treated with therapeutic dose of enoxaparin, and subsequently developed acute embolic occlusion of right femoral artery that lead to an above knee amputation. To our knowledge, left ventricular thromboembolism complicated with acute embolic ischemia in persons living with HIV is extremely rare. The presenting case will definitely add to the current body of knowledge and will raise awareness among physicians, in recognizing the rare association between HIV and arterial thromboembolism.
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spelling pubmed-82607512021-07-12 Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV Chan, Kok Hoe Ramahi, Amr Lim, Su Lin Ahmed, Eyad Suleiman, Addi Slim, Jihad Shaaban, Hamid S Radiol Case Rep Case Report Left ventricular thrombus typically occurs in patients with impaired left ventricular function such as aneurysm, dilated cardiomyopathy, or post-myocardial infarction. Untreated HIV infection is known to increase the risk of venous thromboembolism and cardiovascular disease. However, the pathophysiology remains uncertain; some studies have proposed chronic inflammation as the underlying etiology. Nonetheless, left ventricular thrombus is extremely rare among persons living with HIV with no known underlying cardiac disease. Herein, we report an unusual case of a 55-year-old homeless and heterosexual male with past medical history of HIV, who has mildly reduced left ventricular function and a nonmobile, medium size left ventricular thrombus. Patient was initially treated with therapeutic dose of enoxaparin, and subsequently developed acute embolic occlusion of right femoral artery that lead to an above knee amputation. To our knowledge, left ventricular thromboembolism complicated with acute embolic ischemia in persons living with HIV is extremely rare. The presenting case will definitely add to the current body of knowledge and will raise awareness among physicians, in recognizing the rare association between HIV and arterial thromboembolism. Elsevier 2021-07-01 /pmc/articles/PMC8260751/ /pubmed/34257771 http://dx.doi.org/10.1016/j.radcr.2021.05.068 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chan, Kok Hoe
Ramahi, Amr
Lim, Su Lin
Ahmed, Eyad
Suleiman, Addi
Slim, Jihad
Shaaban, Hamid S
Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
title Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
title_full Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
title_fullStr Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
title_full_unstemmed Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
title_short Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
title_sort left ventricular thrombus complicated by acute limb ischemia in a patient with hiv
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260751/
https://www.ncbi.nlm.nih.gov/pubmed/34257771
http://dx.doi.org/10.1016/j.radcr.2021.05.068
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