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Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment

The covid-19 pandemic has been affecting many countries across the world and lost precious lives. Most patients suffer from respiratory disease which progresses to the severe acute respiratory syndrome, termed as SARS-CoV-2 pneumonia. A systemic inflammatory response occurs in SARS-CoV-2 pneumonia s...

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Autores principales: Gupta, Sweety, Ahuja, Rachit, Sharma, Nidhi, Singh, Pragya, Verma, Swati, Gupta, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261133/
https://www.ncbi.nlm.nih.gov/pubmed/34260977
http://dx.doi.org/10.1016/j.rmed.2021.106531
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author Gupta, Sweety
Ahuja, Rachit
Sharma, Nidhi
Singh, Pragya
Verma, Swati
Gupta, Manoj
author_facet Gupta, Sweety
Ahuja, Rachit
Sharma, Nidhi
Singh, Pragya
Verma, Swati
Gupta, Manoj
author_sort Gupta, Sweety
collection PubMed
description The covid-19 pandemic has been affecting many countries across the world and lost precious lives. Most patients suffer from respiratory disease which progresses to the severe acute respiratory syndrome, termed as SARS-CoV-2 pneumonia. A systemic inflammatory response occurs in SARS-CoV-2 pneumonia severely ill patients, The inflammation process if uncontrolled has a detrimental effect, and the release of cytokines play an important role leading to lung fibrosis. Radiation therapy used in low doses has an anti-inflammatory and immunomodulatory effect. Its low cost, wider availability, and decreased risk of acute side effects can reduce the burden on the health care system.
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spelling pubmed-82611332021-07-07 Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment Gupta, Sweety Ahuja, Rachit Sharma, Nidhi Singh, Pragya Verma, Swati Gupta, Manoj Respir Med Short Review The covid-19 pandemic has been affecting many countries across the world and lost precious lives. Most patients suffer from respiratory disease which progresses to the severe acute respiratory syndrome, termed as SARS-CoV-2 pneumonia. A systemic inflammatory response occurs in SARS-CoV-2 pneumonia severely ill patients, The inflammation process if uncontrolled has a detrimental effect, and the release of cytokines play an important role leading to lung fibrosis. Radiation therapy used in low doses has an anti-inflammatory and immunomodulatory effect. Its low cost, wider availability, and decreased risk of acute side effects can reduce the burden on the health care system. Elsevier Ltd. 2021-09 2021-07-07 /pmc/articles/PMC8261133/ /pubmed/34260977 http://dx.doi.org/10.1016/j.rmed.2021.106531 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Review
Gupta, Sweety
Ahuja, Rachit
Sharma, Nidhi
Singh, Pragya
Verma, Swati
Gupta, Manoj
Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment
title Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment
title_full Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment
title_fullStr Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment
title_full_unstemmed Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment
title_short Low dose lung radiotherapy for COVID-19 pneumonia: A potential treatment
title_sort low dose lung radiotherapy for covid-19 pneumonia: a potential treatment
topic Short Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261133/
https://www.ncbi.nlm.nih.gov/pubmed/34260977
http://dx.doi.org/10.1016/j.rmed.2021.106531
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