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Tumor Mutation Burden Predicts Relapse in Papillary Thyroid Carcinoma With Changes in Genes and Immune Microenvironment

BACKGROUND: The risk factors of papillary thyroid carcinoma (PTC) recurrence are meaningful for patients and clinicians. Tumor mutation burden (TMB) has been a biomarker for the effectiveness of immune checkpoint inhibitor (ICI) and prognosis in cancer. However, the role of TMB and its latent signif...

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Detalles Bibliográficos
Autores principales: Guo, Mengli, Chen, Zhen, Li, Yayi, Li, Sijin, Shen, Fei, Gan, Xiaoxiong, Feng, Jianhua, Cai, Wensong, Liu, Qingzhi, Xu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261145/
https://www.ncbi.nlm.nih.gov/pubmed/34248843
http://dx.doi.org/10.3389/fendo.2021.674616