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The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions

Compared with the young, the elderly (age greater than or equal to 60 years old) vulnerable road users (VRUs) face a greater risk of injury or death in a traffic accident. A contributing vulnerability is the aging processes that affect their brain structure. The purpose of this study was to investig...

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Autores principales: Wu, He, Han, Yong, Pan, Di, Wang, Bingyu, Huang, Hongwu, Mizuno, Koji, Thomson, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261157/
https://www.ncbi.nlm.nih.gov/pubmed/34249884
http://dx.doi.org/10.3389/fbioe.2021.682015
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author Wu, He
Han, Yong
Pan, Di
Wang, Bingyu
Huang, Hongwu
Mizuno, Koji
Thomson, Robert
author_facet Wu, He
Han, Yong
Pan, Di
Wang, Bingyu
Huang, Hongwu
Mizuno, Koji
Thomson, Robert
author_sort Wu, He
collection PubMed
description Compared with the young, the elderly (age greater than or equal to 60 years old) vulnerable road users (VRUs) face a greater risk of injury or death in a traffic accident. A contributing vulnerability is the aging processes that affect their brain structure. The purpose of this study was to investigate the injury mechanisms and establish head AIS 4+ injury tolerances for the elderly VRUs based on various head injury criteria. A total of 30 elderly VRUs accidents with detailed injury records and video information were selected and the VRUs’ kinematics and head injuries were reconstructed by combining a multi-body system model (PC-Crash and MADYMO) and the THUMS (Ver. 4.0.2) FE models. Four head kinematic-based injury predictors (linear acceleration, angular velocity, angular acceleration, and head injury criteria) and three brain tissue injury criteria (coup pressure, maximum principal strain, and cumulative strain damage measure) were studied. The correlation between injury predictors and injury risk was developed using logistical regression models for each criterion. The results show that the calculated thresholds for head injury for the kinematic criteria were lower than those reported in previous literature studies. For the brain tissue level criteria, the thresholds calculated in this study were generally similar to those of previous studies except for the coup pressure. The models had higher (>0.8) area under curve values for receiver operator characteristics, indicating good predictive power. This study could provide additional support for understanding brain injury thresholds in elderly people.
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spelling pubmed-82611572021-07-08 The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions Wu, He Han, Yong Pan, Di Wang, Bingyu Huang, Hongwu Mizuno, Koji Thomson, Robert Front Bioeng Biotechnol Bioengineering and Biotechnology Compared with the young, the elderly (age greater than or equal to 60 years old) vulnerable road users (VRUs) face a greater risk of injury or death in a traffic accident. A contributing vulnerability is the aging processes that affect their brain structure. The purpose of this study was to investigate the injury mechanisms and establish head AIS 4+ injury tolerances for the elderly VRUs based on various head injury criteria. A total of 30 elderly VRUs accidents with detailed injury records and video information were selected and the VRUs’ kinematics and head injuries were reconstructed by combining a multi-body system model (PC-Crash and MADYMO) and the THUMS (Ver. 4.0.2) FE models. Four head kinematic-based injury predictors (linear acceleration, angular velocity, angular acceleration, and head injury criteria) and three brain tissue injury criteria (coup pressure, maximum principal strain, and cumulative strain damage measure) were studied. The correlation between injury predictors and injury risk was developed using logistical regression models for each criterion. The results show that the calculated thresholds for head injury for the kinematic criteria were lower than those reported in previous literature studies. For the brain tissue level criteria, the thresholds calculated in this study were generally similar to those of previous studies except for the coup pressure. The models had higher (>0.8) area under curve values for receiver operator characteristics, indicating good predictive power. This study could provide additional support for understanding brain injury thresholds in elderly people. Frontiers Media S.A. 2021-06-23 /pmc/articles/PMC8261157/ /pubmed/34249884 http://dx.doi.org/10.3389/fbioe.2021.682015 Text en Copyright © 2021 Wu, Han, Pan, Wang, Huang, Mizuno and Thomson. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Wu, He
Han, Yong
Pan, Di
Wang, Bingyu
Huang, Hongwu
Mizuno, Koji
Thomson, Robert
The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions
title The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions
title_full The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions
title_fullStr The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions
title_full_unstemmed The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions
title_short The Head AIS 4+ Injury Thresholds for the Elderly Vulnerable Road User Based on Detailed Accident Reconstructions
title_sort head ais 4+ injury thresholds for the elderly vulnerable road user based on detailed accident reconstructions
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261157/
https://www.ncbi.nlm.nih.gov/pubmed/34249884
http://dx.doi.org/10.3389/fbioe.2021.682015
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