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A Peptide Vaccine Candidate Tailored to Individuals' Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects
Long-term immunity to coronaviruses likely stems from T cell activity. We present here a novel approach for the selection of immunoprevalent SARS-CoV-2-derived T cell epitopes using an in silico cohort of HLA-genotyped individuals with different ethnicities. Nine 30-mer peptides derived from the fou...
Autores principales: | Somogyi, Eszter, Csiszovszki, Zsolt, Molnár, Levente, Lőrincz, Orsolya, Tóth, József, Pattijn, Sofie, Schockaert, Jana, Mazy, Aurélie, Miklós, István, Pántya, Katalin, Páles, Péter, Tőke, Enikő R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261158/ https://www.ncbi.nlm.nih.gov/pubmed/34249101 http://dx.doi.org/10.3389/fgene.2021.684152 |
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