Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo

MicroRNAs (miRNAs) regulate gene expression by post-transcriptional inhibition of target genes. Proangiogenic small extracellular vesicles (sEVs; popularly identified with the name “exosomes”) with a composite cargo of miRNAs are secreted by cultured stem cells and present in human biological fluids...

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Detalles Bibliográficos
Autores principales: Aday, Sezin, Hazan-Halevy, Inbal, Chamorro-Jorganes, Aranzazu, Anwar, Maryam, Goldsmith, Meir, Beazley-Long, Nicholas, Sahoo, Susmita, Dogra, Navneet, Sweaad, Walid, Catapano, Francesco, Ozaki-Tan, Sho, Angelini, Gianni D., Madeddu, Paolo, Benest, Andrew V., Peer, Dan, Emanueli, Costanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261169/
https://www.ncbi.nlm.nih.gov/pubmed/33744469
http://dx.doi.org/10.1016/j.ymthe.2021.03.015

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