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Anti-HER3 monoclonal antibody exerts antitumor activity in a mouse model of colorectal adenocarcinoma

HER3 belongs to the epidermal growth factor receptor (EGFR) family and is known to form an active heterodimer with other three family members EGFR, HER2, and HER4. HER3 is overexpressed in lung, breast, colon, prostate, and gastric cancers. In the present study, we developed and validated an anti-HE...

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Detalles Bibliográficos
Autores principales: Asano, Teizo, Ohishi, Tomokazu, Takei, Junko, Nakamura, Takuro, Nanamiya, Ren, Hosono, Hideki, Tanaka, Tomohiro, Sano, Masato, Harada, Hiroyuki, Kawada, Manabu, Kaneko, Mika K., Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261196/
https://www.ncbi.nlm.nih.gov/pubmed/34184091
http://dx.doi.org/10.3892/or.2021.8124