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Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel

Most biopharmaceutics classification system (BCS) class IV drugs, with poor solubility and inferior permeability, are also substrates of P-glycoprotein (P-gp) and cytochrome P450 (CYP450), leading to their low oral bioavailability. The objective of this study is to explore the potential of using fun...

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Detalles Bibliográficos
Autores principales:	Qin, Lu, Wu, Haiyang, Xu, Enyu, Zhang, Xin, Guan, Jian, Zhao, Ruizhi, Mao, Shirui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2021
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261254/ https://www.ncbi.nlm.nih.gov/pubmed/34276826 http://dx.doi.org/10.1016/j.ajps.2021.02.004

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