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OMICS approaches in cardiovascular diseases: a mini review
Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptom...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korea Genome Organization
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261269/ https://www.ncbi.nlm.nih.gov/pubmed/34261298 http://dx.doi.org/10.5808/gi.21002 |
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author | Sohag, Md. Mehadi Hasan Raqib, Saleh Muhammed Akhmad, Syaefudin Ali |
author_facet | Sohag, Md. Mehadi Hasan Raqib, Saleh Muhammed Akhmad, Syaefudin Ali |
author_sort | Sohag, Md. Mehadi Hasan |
collection | PubMed |
description | Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches which could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect. |
format | Online Article Text |
id | pubmed-8261269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korea Genome Organization |
record_format | MEDLINE/PubMed |
spelling | pubmed-82612692021-07-16 OMICS approaches in cardiovascular diseases: a mini review Sohag, Md. Mehadi Hasan Raqib, Saleh Muhammed Akhmad, Syaefudin Ali Genomics Inform Mini Review Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches which could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect. Korea Genome Organization 2021-06-30 /pmc/articles/PMC8261269/ /pubmed/34261298 http://dx.doi.org/10.5808/gi.21002 Text en (c) 2021, Korea Genome Organization https://creativecommons.org/licenses/by/4.0/(CC) This is an open-access article distributed under the terms of the Creative Commons Attribution license(https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Mini Review Sohag, Md. Mehadi Hasan Raqib, Saleh Muhammed Akhmad, Syaefudin Ali OMICS approaches in cardiovascular diseases: a mini review |
title | OMICS approaches in cardiovascular diseases: a mini review |
title_full | OMICS approaches in cardiovascular diseases: a mini review |
title_fullStr | OMICS approaches in cardiovascular diseases: a mini review |
title_full_unstemmed | OMICS approaches in cardiovascular diseases: a mini review |
title_short | OMICS approaches in cardiovascular diseases: a mini review |
title_sort | omics approaches in cardiovascular diseases: a mini review |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261269/ https://www.ncbi.nlm.nih.gov/pubmed/34261298 http://dx.doi.org/10.5808/gi.21002 |
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