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OMICS approaches in cardiovascular diseases: a mini review

Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptom...

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Autores principales: Sohag, Md. Mehadi Hasan, Raqib, Saleh Muhammed, Akhmad, Syaefudin Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261269/
https://www.ncbi.nlm.nih.gov/pubmed/34261298
http://dx.doi.org/10.5808/gi.21002
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author Sohag, Md. Mehadi Hasan
Raqib, Saleh Muhammed
Akhmad, Syaefudin Ali
author_facet Sohag, Md. Mehadi Hasan
Raqib, Saleh Muhammed
Akhmad, Syaefudin Ali
author_sort Sohag, Md. Mehadi Hasan
collection PubMed
description Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches which could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect.
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spelling pubmed-82612692021-07-16 OMICS approaches in cardiovascular diseases: a mini review Sohag, Md. Mehadi Hasan Raqib, Saleh Muhammed Akhmad, Syaefudin Ali Genomics Inform Mini Review Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches which could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect. Korea Genome Organization 2021-06-30 /pmc/articles/PMC8261269/ /pubmed/34261298 http://dx.doi.org/10.5808/gi.21002 Text en (c) 2021, Korea Genome Organization https://creativecommons.org/licenses/by/4.0/(CC) This is an open-access article distributed under the terms of the Creative Commons Attribution license(https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Mini Review
Sohag, Md. Mehadi Hasan
Raqib, Saleh Muhammed
Akhmad, Syaefudin Ali
OMICS approaches in cardiovascular diseases: a mini review
title OMICS approaches in cardiovascular diseases: a mini review
title_full OMICS approaches in cardiovascular diseases: a mini review
title_fullStr OMICS approaches in cardiovascular diseases: a mini review
title_full_unstemmed OMICS approaches in cardiovascular diseases: a mini review
title_short OMICS approaches in cardiovascular diseases: a mini review
title_sort omics approaches in cardiovascular diseases: a mini review
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261269/
https://www.ncbi.nlm.nih.gov/pubmed/34261298
http://dx.doi.org/10.5808/gi.21002
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