Cargando…
The Curcumin Analog GO-Y030 Controls the Generation and Stability of Regulatory T Cells
Regulatory T cells (Tregs) play a crucial role in preventing antitumor immune responses in cancer tissues. Cancer tissues produce large amounts of transforming growth factor beta (TGF-β), which promotes the generation of Foxp3(+) Tregs from naïve CD4(+) T cells in the local tumor microenvironment. T...
Autores principales: | MaruYama, Takashi, Kobayashi, Shuhei, Nakatsukasa, Hiroko, Moritoki, Yuki, Taguchi, Daiki, Sunagawa, Yoichi, Morimoto, Tatsuya, Asao, Atsuko, Jin, Wenwen, Owada, Yuji, Ishii, Naoto, Iwabuchi, Yoshiharu, Yoshimura, Akihiko, Chen, WanJun, Shibata, Hiroyuki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261301/ https://www.ncbi.nlm.nih.gov/pubmed/34248973 http://dx.doi.org/10.3389/fimmu.2021.687669 |
Ejemplares similares
-
Curcumin analog GO‐Y030 boosts the efficacy of anti‐PD‐1 cancer immunotherapy
por: MaruYama, Takashi, et al.
Publicado: (2021) -
The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice
por: Shimizu, Kana, et al.
Publicado: (2020) -
Pyrolyzed deketene curcumin controls regulatory T cell generation and gastric cancer metabolism cooperate with 2-deoxy-d-glucose
por: MaruYama, Takashi, et al.
Publicado: (2023) -
Structure-Activity Relationships of the Antitumor C(5)-Curcuminoid GO-Y030
por: Kohyama, Aki, et al.
Publicado: (2015) -
Fatty acid‐binding protein 3 controls contact hypersensitivity through regulating skin dermal Vγ4(+) γ/δ T cell in a murine model
por: Kobayashi, Shuhei, et al.
Publicado: (2020)