Cargando…
Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review
BACKGROUND: The main objective of this study was to evaluate the various instruments available to evaluate the quality of life (QoL) in patients diagnosed with non-muscle invasive bladder cancer (NMIBC) undergoing surveillance. METHODS: A PubMed literature review was carried out with query terms (“U...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261437/ https://www.ncbi.nlm.nih.gov/pubmed/34295759 http://dx.doi.org/10.21037/tau-20-1333 |
_version_ | 1783719012824252416 |
---|---|
author | Nayak, Arvind Cresswell, Joanne Mariappan, Paramananthan |
author_facet | Nayak, Arvind Cresswell, Joanne Mariappan, Paramananthan |
author_sort | Nayak, Arvind |
collection | PubMed |
description | BACKGROUND: The main objective of this study was to evaluate the various instruments available to evaluate the quality of life (QoL) in patients diagnosed with non-muscle invasive bladder cancer (NMIBC) undergoing surveillance. METHODS: A PubMed literature review was carried out with query terms (“Urinary Bladder Neoplasms” [Mesh] OR “Bladder malignancy”) AND (“quality of life”) including all studies up to June 2020. This resulted in 576 peer-reviewed articles. A further 12 articles from additional sources were included. A total of 473 articles were eliminated due to lack of relevance to the topic of concern. A further 93 articles evaluating NMIBC and articles evaluating Radiotherapy were excluded and a total of 22 studies were studied. RESULTS: In total, 22 studies were identified. The vast majority of studies were prospective descriptive studies (n=9), while there were 7 cross-sectional surveys and 6 randomised controlled trials. Most studies evaluated the impact of intravesical treatment on QoL. NMIBC survivors had significantly lower QoL compared to the general population, Surveillance strategies involving repeated intravesical therapies and cystoscopies have a negative impact on QoL with impaired physical function and mental health. CONCLUSIONS: This article emphasizes the importance of assessing the QoL in patients with NMIBC undergoing long term surveillance, as they represent the majority of bladder cancer patients. Development and validation of specific instruments to measure QoL in patients with NMIBC are desperately needed to assess, better understand, and manage the burden of disease and healthcare in this group of patients. |
format | Online Article Text |
id | pubmed-8261437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-82614372021-07-21 Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review Nayak, Arvind Cresswell, Joanne Mariappan, Paramananthan Transl Androl Urol Original Article on Expectant Management in Genitourinary Malignancies (Prostate, Bladder, Kidney) BACKGROUND: The main objective of this study was to evaluate the various instruments available to evaluate the quality of life (QoL) in patients diagnosed with non-muscle invasive bladder cancer (NMIBC) undergoing surveillance. METHODS: A PubMed literature review was carried out with query terms (“Urinary Bladder Neoplasms” [Mesh] OR “Bladder malignancy”) AND (“quality of life”) including all studies up to June 2020. This resulted in 576 peer-reviewed articles. A further 12 articles from additional sources were included. A total of 473 articles were eliminated due to lack of relevance to the topic of concern. A further 93 articles evaluating NMIBC and articles evaluating Radiotherapy were excluded and a total of 22 studies were studied. RESULTS: In total, 22 studies were identified. The vast majority of studies were prospective descriptive studies (n=9), while there were 7 cross-sectional surveys and 6 randomised controlled trials. Most studies evaluated the impact of intravesical treatment on QoL. NMIBC survivors had significantly lower QoL compared to the general population, Surveillance strategies involving repeated intravesical therapies and cystoscopies have a negative impact on QoL with impaired physical function and mental health. CONCLUSIONS: This article emphasizes the importance of assessing the QoL in patients with NMIBC undergoing long term surveillance, as they represent the majority of bladder cancer patients. Development and validation of specific instruments to measure QoL in patients with NMIBC are desperately needed to assess, better understand, and manage the burden of disease and healthcare in this group of patients. AME Publishing Company 2021-06 /pmc/articles/PMC8261437/ /pubmed/34295759 http://dx.doi.org/10.21037/tau-20-1333 Text en 2021 Translational Andrology and Urology. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Original Article on Expectant Management in Genitourinary Malignancies (Prostate, Bladder, Kidney) Nayak, Arvind Cresswell, Joanne Mariappan, Paramananthan Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
title | Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
title_full | Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
title_fullStr | Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
title_full_unstemmed | Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
title_short | Quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
title_sort | quality of life in patients undergoing surveillance for non-muscle invasive bladder cancer—a systematic review |
topic | Original Article on Expectant Management in Genitourinary Malignancies (Prostate, Bladder, Kidney) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261437/ https://www.ncbi.nlm.nih.gov/pubmed/34295759 http://dx.doi.org/10.21037/tau-20-1333 |
work_keys_str_mv | AT nayakarvind qualityoflifeinpatientsundergoingsurveillancefornonmuscleinvasivebladdercancerasystematicreview AT cresswelljoanne qualityoflifeinpatientsundergoingsurveillancefornonmuscleinvasivebladdercancerasystematicreview AT mariappanparamananthan qualityoflifeinpatientsundergoingsurveillancefornonmuscleinvasivebladdercancerasystematicreview |