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Programmable Unlocking Nano‐Matryoshka‐CRISPR Precisely Reverses Immunosuppression to Unleash Cascade Amplified Adaptive Immune Response

Immune checkpoint blockade (ICB) is an attractive option in cancer therapy, but its efficacy is still less than expected due to the transient and incomplete blocking and the low responsiveness. Herein, an unprecedented programmable unlocking nano‐matryoshka‐CRISPR system (PUN) targeting programmed c...

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Detalles Bibliográficos
Autores principales:	Yang, Jin, Li, Zhike, Shen, Meiling, Wang, Yan, Wang, Li, Li, Jiamiao, Yang, Wen, Li, Jie, Li, Haijun, Wang, Xinxin, Wu, Qinjie, Gong, Changyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261501/ https://www.ncbi.nlm.nih.gov/pubmed/34258164 http://dx.doi.org/10.1002/advs.202100292

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