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A straightforward conversion of 1,4-quinones into polycyclic pyrazoles via [3 + 2]-cycloaddition with fluorinated nitrile imines

In-situ-generated N-aryl nitrile imines derived from trifluoroacetonitrile efficiently react with polycyclic 1,4-quinones, yielding fused pyrazole derivatives as the exclusive products. The reactions proceed via the initially formed [3 + 2]-cycloadducts, which undergo spontaneous aerial oxidation to...

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Detalles Bibliográficos
Autores principales:	Utecht-Jarzyńska, Greta, Nagła, Karolina, Mlostoń, Grzegorz, Heimgartner, Heinz, Palusiak, Marcin, Jasiński, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2021
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261526/ https://www.ncbi.nlm.nih.gov/pubmed/34285722 http://dx.doi.org/10.3762/bjoc.17.108

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