Low dose dexamethasone as treatment for women with heavy menstrual bleeding: A response-adaptive randomised placebo-controlled dose-finding parallel group trial (DexFEM)

BACKGROUND: The symptom of heavy menstrual bleeding (HMB) diminishes quality-of-life for many mid-age women and imposes substantial societal burden. We investigated our hypothesis that HMB reflects impaired endometrial vasoconstriction due to endometrial glucocorticoid deficiency. Does reversing thi...

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Detalles Bibliográficos
Autores principales: Warner, Pamela, Whitaker, Lucy Harriet Ravenscroft, Parker, Richard Anthony, Weir, Christopher John, Douglas, Anne, Hansen, Christian Holm, Madhra, Mayank, Hillier, Stephen Gilbert, Saunders, Philippa Tansy Kemp, Iredale, John Peter, Semple, Scott, Slayden, Ov Daniel, Walker, Brian Robert, Critchley, Hilary Octavia Dawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261537/
https://www.ncbi.nlm.nih.gov/pubmed/34218053
http://dx.doi.org/10.1016/j.ebiom.2021.103434

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