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Direct synthesis of pentasubstituted pyrroles and hexasubstituted pyrrolines from propargyl sulfonylamides and allenamides

Multisubstituted pyrroles are important fragments that appear in many bioactive small molecule scaffolds. Efficient synthesis of multisubstituted pyrroles with different substituents from easily accessible starting materials is challenging. Herein, we describe a metal-free method for the preparation...

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Detalles Bibliográficos
Autores principales: Ye, Changqing, Jiao, Yihang, Chiou, Mong-Feng, Li, Yajun, Bao, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261710/
https://www.ncbi.nlm.nih.gov/pubmed/34276946
http://dx.doi.org/10.1039/d1sc02090k