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Sarcopenia in hemodialysis patients from Buenos Aires, Argentina
OBJECTIVES: Sarcopenia is the loss of skeletal muscle mass and function that occurs with aging that can lead to greater morbidity and mortality. Chronic kidney disease and hemodialysis (HD) favors the development of sarcopenia. We studied the prevalence of sarcopenia and its components using Europea...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Osteoporosis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261721/ https://www.ncbi.nlm.nih.gov/pubmed/34278003 http://dx.doi.org/10.1016/j.afos.2021.04.001 |
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author | Abdala, Ruben Elena del Valle, Elisa Negri, Armando Luis Bridoux, Pablo Paganti, Luciana Gonzalez Bravo, Marina Sintado, Luis Di Rienzo, Paula Schiavelli, Omar R. Zanchetta, Maria Belén Guinsburg, Adrián |
author_facet | Abdala, Ruben Elena del Valle, Elisa Negri, Armando Luis Bridoux, Pablo Paganti, Luciana Gonzalez Bravo, Marina Sintado, Luis Di Rienzo, Paula Schiavelli, Omar R. Zanchetta, Maria Belén Guinsburg, Adrián |
author_sort | Abdala, Ruben |
collection | PubMed |
description | OBJECTIVES: Sarcopenia is the loss of skeletal muscle mass and function that occurs with aging that can lead to greater morbidity and mortality. Chronic kidney disease and hemodialysis (HD) favors the development of sarcopenia. We studied the prevalence of sarcopenia and its components using European Working Group on Sarcopenia in Elderly People 2 proposed criteria and risk factors for its development in HD patients. METHODS: In 100 adult HD patients, we evaluated: hand grip strength (HGS), muscle mass by dual energy X-ray absorptiometry and physical performance (gait-speed and sit-stand test). RESULTS: Sixty patients were male and 40 were female; mean age 55.6 years. Prevalence of sarcopenia was 16% (11.1% in males and 25% in females; P = 0.05); 7% had severe sarcopenia. Prevalence of low HGS was 33% in males and 28% in females; low muscle mass was 30% in males but 70% in females and low physical performance 23% in males and 45% in females. Falls were reported by 23 patients. Patients with lower HGS had a higher prevalence of falls in the last year (40% two or more falls; P = 0.03). Only females with sarcopenia had lower bone mineral content. Neither age, body mass index, time on dialysis, or prevalence of diabetes predicted sarcopenia. CONCLUSIONS: A significant proportion of dialysis patients had sarcopenia, more frequent in females. Low HGS was associated with a higher prevalence of falls. Only females with sarcopenia had lower bone mineral content. |
format | Online Article Text |
id | pubmed-8261721 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Osteoporosis |
record_format | MEDLINE/PubMed |
spelling | pubmed-82617212021-07-16 Sarcopenia in hemodialysis patients from Buenos Aires, Argentina Abdala, Ruben Elena del Valle, Elisa Negri, Armando Luis Bridoux, Pablo Paganti, Luciana Gonzalez Bravo, Marina Sintado, Luis Di Rienzo, Paula Schiavelli, Omar R. Zanchetta, Maria Belén Guinsburg, Adrián Osteoporos Sarcopenia Original Article OBJECTIVES: Sarcopenia is the loss of skeletal muscle mass and function that occurs with aging that can lead to greater morbidity and mortality. Chronic kidney disease and hemodialysis (HD) favors the development of sarcopenia. We studied the prevalence of sarcopenia and its components using European Working Group on Sarcopenia in Elderly People 2 proposed criteria and risk factors for its development in HD patients. METHODS: In 100 adult HD patients, we evaluated: hand grip strength (HGS), muscle mass by dual energy X-ray absorptiometry and physical performance (gait-speed and sit-stand test). RESULTS: Sixty patients were male and 40 were female; mean age 55.6 years. Prevalence of sarcopenia was 16% (11.1% in males and 25% in females; P = 0.05); 7% had severe sarcopenia. Prevalence of low HGS was 33% in males and 28% in females; low muscle mass was 30% in males but 70% in females and low physical performance 23% in males and 45% in females. Falls were reported by 23 patients. Patients with lower HGS had a higher prevalence of falls in the last year (40% two or more falls; P = 0.03). Only females with sarcopenia had lower bone mineral content. Neither age, body mass index, time on dialysis, or prevalence of diabetes predicted sarcopenia. CONCLUSIONS: A significant proportion of dialysis patients had sarcopenia, more frequent in females. Low HGS was associated with a higher prevalence of falls. Only females with sarcopenia had lower bone mineral content. Korean Society of Osteoporosis 2021-06 2021-05-08 /pmc/articles/PMC8261721/ /pubmed/34278003 http://dx.doi.org/10.1016/j.afos.2021.04.001 Text en © 2021 The Korean Society of Osteoporosis. Publishing services by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Abdala, Ruben Elena del Valle, Elisa Negri, Armando Luis Bridoux, Pablo Paganti, Luciana Gonzalez Bravo, Marina Sintado, Luis Di Rienzo, Paula Schiavelli, Omar R. Zanchetta, Maria Belén Guinsburg, Adrián Sarcopenia in hemodialysis patients from Buenos Aires, Argentina |
title | Sarcopenia in hemodialysis patients from Buenos Aires, Argentina |
title_full | Sarcopenia in hemodialysis patients from Buenos Aires, Argentina |
title_fullStr | Sarcopenia in hemodialysis patients from Buenos Aires, Argentina |
title_full_unstemmed | Sarcopenia in hemodialysis patients from Buenos Aires, Argentina |
title_short | Sarcopenia in hemodialysis patients from Buenos Aires, Argentina |
title_sort | sarcopenia in hemodialysis patients from buenos aires, argentina |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261721/ https://www.ncbi.nlm.nih.gov/pubmed/34278003 http://dx.doi.org/10.1016/j.afos.2021.04.001 |
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