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Stable trimer formation of spike protein from porcine epidemic diarrhea virus improves the efficiency of secretory production in silkworms and induces neutralizing antibodies in mice
Porcine epidemic diarrhea virus (PEDV) is a highly infectious pathogen of watery diarrhea that causes serious economic loss to the swine industry worldwide. Especially because of the high mortality rate in neonatal piglets, a vaccine with less production cost and high protective effect against PEDV...
Autores principales: | Masuda, Akitsu, Lee, Jae Man, Miyata, Takeshi, Ebihara, Takeru, Kakino, Kohei, Hino, Masato, Fujita, Ryosuke, Mon, Hiroaki, Kusakabe, Takahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261802/ https://www.ncbi.nlm.nih.gov/pubmed/34233749 http://dx.doi.org/10.1186/s13567-021-00971-5 |
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