Enzyme mediated incorporation of zirconium-89 or copper-64 into a fragment antibody for same day imaging of epidermal growth factor receptor

Identification of tumors which over-express Epidermal Growth Factor Receptor (EGFR) is important in selecting patients for anti-EGFR therapies. Enzymatic bioconjugation was used to introduce positron-emitting radionuclides ((89)Zr, (64)Cu) into an anti-EGFR antibody fragment for Positron Emission To...

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Detalles Bibliográficos
Autores principales: Rudd, Stacey E., Van Zuylekom, Jessica K., Raicevic, Anna, Pearce, Lesley A., Cullinane, Carleen, Williams, Charlotte C., Adams, Timothy E., Hicks, Rodney J., Donnelly, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261882/
https://www.ncbi.nlm.nih.gov/pubmed/34276928
http://dx.doi.org/10.1039/d1sc01422f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261882/
https://www.ncbi.nlm.nih.gov/pubmed/34276928
http://dx.doi.org/10.1039/d1sc01422f

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