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Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects
BACKGROUND: Metformin is a commonly used antidiabetic medication which has demonstrated promise as an anticancer agent alone and in combination with conventional treatment regimens. There is increasing evidence that metformin can also generate immunomodulatory effects in solid tumors and is currentl...
Autores principales: | Veeramachaneni, Ratna, Yu, Wangjie, Newton, Jared M, Kemnade, Jan O, Skinner, Heath D, Sikora, Andrew G, Sandulache, Vlad C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261884/ https://www.ncbi.nlm.nih.gov/pubmed/34230113 http://dx.doi.org/10.1136/jitc-2021-002773 |
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