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Cangrelor ameliorates CLP-induced pulmonary injury in sepsis by inhibiting GPR17

BACKGROUND: Sepsis is a common complication of severe wound injury and infection, with a very high mortality rate. The P2Y12 receptor inhibitor, cangrelor, is an antagonist anti-platelet drug. METHODS: In our study, we investigated the protective mechanisms of cangrelor in CLP-induced pulmonary inju...

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Detalles Bibliográficos
Autores principales:	Luo, Qiancheng, Liu, Rui, Qu, Kaili, Liu, Guorong, Hang, Min, Chen, Guo, Xu, Lei, Jin, Qinqin, Guo, Dongfeng, Kang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262027/ https://www.ncbi.nlm.nih.gov/pubmed/34229761 http://dx.doi.org/10.1186/s40001-021-00536-4

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