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Hybrid Capture-based Genomic Profiling of Circulating Tumor DNA From Patients With Advanced Ovarian Cancer

Objective: We conducted this study to characterize somatic genomic alterations in circulating tumor DNA (ctDNA) from patients with ovarian cancer and compare GAs detected in ctDNA with tissue databases. Methods: Hybrid capture-next generation sequencing genomic profiling of 150 genes was performed o...

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Detalles Bibliográficos
Autores principales: Shen, Wenbin, Shan, Boer, Liang, Shanhui, Zhang, Junling, Yu, Yangyang, Zhang, Yuzi, Wang, Guoqiang, Bai, Yuezong, Qian, Bing, Lu, Jin, Jiang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262155/
https://www.ncbi.nlm.nih.gov/pubmed/34257528
http://dx.doi.org/10.3389/pore.2021.581534