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Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation

[Image: see text] A central tenet in the design of vaccines is the display of native-like antigens in the elicitation of protective immunity. The abundance of N-linked glycans across the SARS-CoV-2 spike protein is a potential source of heterogeneity among the many different vaccine candidates under...

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Detalles Bibliográficos
Autores principales: Allen, Joel D., Chawla, Himanshi, Samsudin, Firdaus, Zuzic, Lorena, Shivgan, Aishwary Tukaram, Watanabe, Yasunori, He, Wan-ting, Callaghan, Sean, Song, Ge, Yong, Peter, Brouwer, Philip J. M., Song, Yutong, Cai, Yongfei, Duyvesteyn, Helen M. E., Malinauskas, Tomas, Kint, Joeri, Pino, Paco, Wurm, Maria J., Frank, Martin, Chen, Bing, Stuart, David I., Sanders, Rogier W., Andrabi, Raiees, Burton, Dennis R., Li, Sai, Bond, Peter J., Crispin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262170/
https://www.ncbi.nlm.nih.gov/pubmed/34213308
http://dx.doi.org/10.1021/acs.biochem.1c00279