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Zinc-Embedded Polyamide Fabrics Inactivate SARS-CoV-2 and Influenza A Virus
[Image: see text] Influenza A viruses (IAV) and SARS-CoV-2 can spread via liquid droplets and aerosols. Face masks and other personal protective equipment (PPE) can act as barriers that prevent the spread of these viruses. However, IAV and SARS-CoV-2 are stable for hours on various materials, which...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262172/ https://www.ncbi.nlm.nih.gov/pubmed/34180223 http://dx.doi.org/10.1021/acsami.1c04412 |
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author | Gopal, Vikram Nilsson-Payant, Benjamin E. French, Hollie Siegers, Jurre Y. Yung, Wai-shing Hardwick, Matthew te Velthuis, Aartjan J. W. |
author_facet | Gopal, Vikram Nilsson-Payant, Benjamin E. French, Hollie Siegers, Jurre Y. Yung, Wai-shing Hardwick, Matthew te Velthuis, Aartjan J. W. |
author_sort | Gopal, Vikram |
collection | PubMed |
description | [Image: see text] Influenza A viruses (IAV) and SARS-CoV-2 can spread via liquid droplets and aerosols. Face masks and other personal protective equipment (PPE) can act as barriers that prevent the spread of these viruses. However, IAV and SARS-CoV-2 are stable for hours on various materials, which makes frequent and correct disposal of these PPE important. Metal ions embedded into PPE may inactivate respiratory viruses, but confounding factors such as adsorption of viruses make measuring and optimizing the inactivation characteristics difficult. Here, we used polyamide 6.6 (PA66) fibers containing embedded zinc ions and systematically investigated if these fibers can adsorb and inactivate SARS-CoV-2 and IAV H1N1 when woven into a fabric. We found that our PA66-based fabric decreased the IAV H1N1 and SARS-CoV-2 titer by approximately 100-fold. Moreover, we found that the zinc content and the virus inactivating property of the fabric remained stable over 50 standardized washes. Overall, these results provide insights into the development of reusable PPE that offer protection against RNA virus spread. |
format | Online Article Text |
id | pubmed-8262172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American
Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-82621722021-07-08 Zinc-Embedded Polyamide Fabrics Inactivate SARS-CoV-2 and Influenza A Virus Gopal, Vikram Nilsson-Payant, Benjamin E. French, Hollie Siegers, Jurre Y. Yung, Wai-shing Hardwick, Matthew te Velthuis, Aartjan J. W. ACS Appl Mater Interfaces [Image: see text] Influenza A viruses (IAV) and SARS-CoV-2 can spread via liquid droplets and aerosols. Face masks and other personal protective equipment (PPE) can act as barriers that prevent the spread of these viruses. However, IAV and SARS-CoV-2 are stable for hours on various materials, which makes frequent and correct disposal of these PPE important. Metal ions embedded into PPE may inactivate respiratory viruses, but confounding factors such as adsorption of viruses make measuring and optimizing the inactivation characteristics difficult. Here, we used polyamide 6.6 (PA66) fibers containing embedded zinc ions and systematically investigated if these fibers can adsorb and inactivate SARS-CoV-2 and IAV H1N1 when woven into a fabric. We found that our PA66-based fabric decreased the IAV H1N1 and SARS-CoV-2 titer by approximately 100-fold. Moreover, we found that the zinc content and the virus inactivating property of the fabric remained stable over 50 standardized washes. Overall, these results provide insights into the development of reusable PPE that offer protection against RNA virus spread. American Chemical Society 2021-06-27 2021-07-07 /pmc/articles/PMC8262172/ /pubmed/34180223 http://dx.doi.org/10.1021/acsami.1c04412 Text en © 2021 The Authors. Published by American Chemical Society Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Gopal, Vikram Nilsson-Payant, Benjamin E. French, Hollie Siegers, Jurre Y. Yung, Wai-shing Hardwick, Matthew te Velthuis, Aartjan J. W. Zinc-Embedded Polyamide Fabrics Inactivate SARS-CoV-2 and Influenza A Virus |
title | Zinc-Embedded
Polyamide Fabrics Inactivate SARS-CoV-2
and Influenza A Virus |
title_full | Zinc-Embedded
Polyamide Fabrics Inactivate SARS-CoV-2
and Influenza A Virus |
title_fullStr | Zinc-Embedded
Polyamide Fabrics Inactivate SARS-CoV-2
and Influenza A Virus |
title_full_unstemmed | Zinc-Embedded
Polyamide Fabrics Inactivate SARS-CoV-2
and Influenza A Virus |
title_short | Zinc-Embedded
Polyamide Fabrics Inactivate SARS-CoV-2
and Influenza A Virus |
title_sort | zinc-embedded
polyamide fabrics inactivate sars-cov-2
and influenza a virus |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262172/ https://www.ncbi.nlm.nih.gov/pubmed/34180223 http://dx.doi.org/10.1021/acsami.1c04412 |
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