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Overexpression of CD44v8-10 in Colon Polyps—A Possible Key to Early Diagnosis

Background and aims: The majority of colorectal cancers arise from detectable adenomatous or serrated lesions. Here we demonstrate how deregulated alternative splicing of CD44 gene in diseased colon mucosa results in downregulation of standard isoform of CD44 gene (CD44s) and upregulation of variant...

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Detalles Bibliográficos
Autores principales: Dastych, Milan, Hubatka, Frantisek, Turanek-Knotigova, Pavlina, Masek, Josef, Kroupa, Radek, Raška, Milan, Turanek, Jaroslav, Prochazka, Lubomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262190/
https://www.ncbi.nlm.nih.gov/pubmed/34257584
http://dx.doi.org/10.3389/pore.2021.614281