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Wnt3a/β-Catenin/CBP Activation in the Progression of Cervical Intraepithelial Neoplasia

Piwil2 reprograms HPV-infected reserve cells in the cervix into tumor-initiated cells (TICs) and upregulates Wnt3a expression sequentially, which leads to cervical intraepithelial neoplasia (CIN) and ultimately squamous cell carcinoma (SCC). However, little is known regarding Wnt signaling in the ma...

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Detalles Bibliográficos
Autores principales: Feng, Dingqing, Lin, Jie, Wang, Wenhui, Yan, Keqin, Liang, Haiyan, Liang, Jing, Yu, Huan, Ling, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262210/
https://www.ncbi.nlm.nih.gov/pubmed/34257574
http://dx.doi.org/10.3389/pore.2021.609620