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Wnt3a/β-Catenin/CBP Activation in the Progression of Cervical Intraepithelial Neoplasia
Piwil2 reprograms HPV-infected reserve cells in the cervix into tumor-initiated cells (TICs) and upregulates Wnt3a expression sequentially, which leads to cervical intraepithelial neoplasia (CIN) and ultimately squamous cell carcinoma (SCC). However, little is known regarding Wnt signaling in the ma...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262210/ https://www.ncbi.nlm.nih.gov/pubmed/34257574 http://dx.doi.org/10.3389/pore.2021.609620 |